Sina Ampholeish

Introduction

This product is a topical nanoliposomal gel 0.4% amphotericin B which produced for the treatment of cutaneous leishmaniasis and can be topically applied. Amphotericin B is the most effective drug for the treatment of fungal and protozoan infections such as leishmaniasis. Due to renal toxicity caused by this drug, liposomal formulations can be used for targeted drug delivery. The liposomal form of this drug reduces its destructive effects on the body and increases its penetration and transfer to the surface of the fungi.

Application

• Treatment of cutaneous leishmaniasis
• Effective in the treatment of topical fungal diseases

Advantage of Using Nanotechnology

Liposomes are the most widely used antimicrobial drug delivery system. The major distinguishing feature of liposomes is its lipid bilayer structure, which mimics cell membranes and can readily fuse with infectious microbes. By directly fusing with bacterial membranes, the drug payloads of liposomes can be released to the cell membranes or the interior of the bacteria.

Certificates and Standards

• NanoScale Certification
• Iran Ministry of Health Certification